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Publications
Sequential List & Download Links

0-9

FRS PhD Thesis UCSD
The Crystal Structure of Cytochrome C2 from R. rubrum and Related Topics in Protein Crystallography
Enzymic Redox Reactions of Cytochrome c.
A Device for the Rapid Measurement of Molecular Model Coordinates for X-ray Crystallography.
A Free Interface Diffusion Technique for the Crystallization of Proteins for X-ray Crystallography.
Involvement in Biology Today
Atomic Coordinates for Ferricytochrome c2 of Rhodospirillum rubrum.
The Structure of Oxidized Cytochrome c2 of Rhodospirillum rubrum.
Structural Bases for Function in Cytochrome c: An Interpretation of Comparative X-ray and Biochemical Data.
Preliminary Crystallographic Data for Cytochrome c' of Rhodopseudomonas palustris.
A Hypothetical Structure for an Intermolecular Electron Transfer Complex of Cytochromes c and b5.

10-19

Structure and Function of Cytochrome c.
The Structure of Chlorobium thiosulfatophilum cytochrome c555: A Primitive Low-potential c-type Cytochrome.
Preliminary Crystallographic Data for Cytochromes c' of Rhodopseudomonas capsulata and Rhodospirillum molischianum.
Structural Convergence During Protein Evolution
Protein Dynamics, Potential Regulation and Redox Coupled Conformational Changes in Cytochrome c.
Structure-Function Relationships in Biological Electron Transport Proteins.
Peptide Models for the Study of Coupled Conformational Properties of Protein Secondary Structures.
Conformations of Twisted Parallel ß-Sheets and the Origin of Chirality in Protein Structures.
Structural and Functional Diversity in 4- a-Helical Proteins.
Structure of Cytochrome c': A Dimeric High-Spin Haem Protein.

20-29

Crystallographic Structure of Rhodospirillum molischianum Ferricytochrome c' at 2.5 Å Resolution.
On the Evolutionary Relationship of 4- a-Helical Heme Proteins.
Conformational and Geometrical Properties of ß - Sheets in Proteins. I. Parallel Sheets.
Conformational and Geometrical Properties of ß - Sheets in Proteins. II. Antiparallel and Mixed b-Sheets.
Conformational and Geometrical Properties of ß - Sheets in Proteins. III. Isotropically Stressed Configurations.
Cytochrome c’: A Dimeric High-Spin Heme Protein.
Conformational Flexibility and Amide Exchange Stability in Protein ß - Sheets.
A Model for Catabolite Activator Protein Binding to Supercoiled DNA.
Preliminary Crystallographic Data for Chromatium Flavocytochrome c552.
The a-Helix Dipole Model and Electrostatic Stabilization of a 4- a-Helical Proteins.

30-39

Transient Kinetics of Electron Transfer Reactions of Flavodoxin: Ionic Strength Dependence of Semiquinone Oxidation by Cytochrome c, Ferricyanide, and Ferri EDTA and Computer Modelling of Reaction Complexes.
Structural Properties of Protein ß-Sheets.
Zubay Biochemistry : Two Chapters on Protein Structure and Function
Electrostatic Orientation During Electron Transfer Between Flavodoxin and Cytochrome c.
Modeling Correlated Motions in Proteins and Implications for Protein Refinement.
Some Minor Refinements on the Richards Optical Comparator and Methods for Model Coordinate Measurement.
Protein Crystallization by Free Interface Diffusion.
Engineering Aspects of Protein Structure.
Anomalous Temperature Factor Behavior and Crystal Lattice Mobility in Cytochrome c’
The 2Å Resolution Structure of a Thermostable Ribonuclease-A Chemically Cross-linked Between Lysine residues 7 and 41.

40-49

The Structure of Ferricytochrome c' from Rhodospirillum molischianum at 1.67 Å Resolution
Lattice Mobility and Anomalous Temperature Factor Behavior in Cytochrome c’.
Preliminary Crystallographic Data for Cross-linked (Lysine 7-Lysine 41) -Ribonuclease A.
Some Design Principles for Structurally Stable Proteins.
Computer Simulations of Biological Interactions and Reactivity.
Molecular Dynamics of a Cytochrome c-Cytochrome b5 Electron Transfer Complex.
Preliminary Crystallographic Data for Streptomyces avidinii Streptavidin.
Use of an Imaging Proportional Counter in Macromolecular Crystallography.
Molecular Factors Stabilizing Protein Crystals.
Structural Polymorphism in Transmembrane Channels.

51-59

Protein Crystal Growth in Microgravity.
Molecular Dynamics Simulation of a Phospholipid Micelle.
Structural Origins of High Affinity Biotin Binding to Streptavidin.
Protein Crystal Growth in Microgravity.
Computational Challenges in Structure-Based Drug Design.
X-Ray Structural Studies of the Cytokine Interleukin 1-ß.
Molecular Modeling with Substructure Libraries Derived From Known Protein Structures.
Crystal Structure of a Retroviral Protease from Avian Myeloblastosis Associated Virus.
A Molecular Dynamics Investigation of the Elastomeric Restoring Force in Elastin.

60-69

Competitor Analogs for Defined T Cell Antigens: Peptides Incorporating a Putative Binding Motif and Polyproline or Polyglycine Spacers.
Protein Engineering and Design: Editorial Overview.
Computational and database retrieval approaches for determining polypeptide conformation.
The Refined Crystal Structure of Bovine Pro-Phospholipase A2 at 1.6 Å Resolution.
An Independent Crystallographic Refinement of Porcine Phospholipase A2 at 2.4 Å Resolution.
Cooperative Ligand Reorientations in Cytochrome c3: A Molecular Dynamics Simulation.
The Identification of Tyrosine as a Common Key Residue in Unrelated H-2Kd Restricted Antigenic Peptides.
Protein Crystal Growth Results for Shuttle Flights STS-26 and STS-29.
Protein Engineering for Molecular Electronics.
Protein Engineering for Molecular Electronics.

70-79

Protein Engineering and Design: Editorial Overview.
Permuteins of interleukin 1ß- a simplified approach for the construction of permuted proteins having new termini.
Crystallographic and Thermodynamic Comparison of Natural and Synthetic Ligands Bound to Streptavidin.
PROBIT: A Statistical Approach to Modeling Proteins from Partial Coordinate Data Using Substructure Libraries.
Structural Studies of the Retroviral Proteinase from Avian Myeloblastosis Associated Virus.
Neural Network for the Detection and Prediction of 3D Structural Motifs in Proteins.
Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin.
Design, Synthesis, and Fabrication of a Novel, Self-Assembling Fibrillar Protein.
Crystallographic and Thermodynamic Comparison of Structurally Diverse Molecules Binding to Streptavidin.
Enhancing the Drug Discovery Process by Integration of High-Throughput Chemistry and Structure-Based Drug Design.

80-89

The integration of Structure-Based Design and Directed Combinatorial Chemstry for New Pharmaceutical Discovery.
Serendipity meets precision: the integration of structure-based drug design and combinatorial chemistry for efficient drug discovery.
In vitro evaluation and crystallographic analysis of a new class of selective, non-amide-based thrombin inhibitors.
Expanding the envelope of structure-based drug design using chemical libraries: application to small-molecule inhibitors of thrombin.
Serine proteases-directed small molecule probe libraries.
Advances in diversity profiling and combinatorial series design.
Amidinohydrazones as Guanidine Bioisosteres: Application to a New Class of Potent, Selective, and Orally Bioavailable, Non-amide-Based Small Molecule Thrombin Inhibitors.
Non-Peptidic Phenyl-Based Thrombin Inhibitors: Exploring Structural Requirements of the S1 Specificity Pocket with Amidines.
Structure-Activity and Crystallographic Analysis of a New Class of Non-amide-Based Thrombin Inhibitor.
High Density Miniaturized Thermal Shift Assay as a General Strategy for Drug Discovery.

90-99

Combinatorial Informatics in the Post-Genomics Era.
Applications of Calorimetric Methods to Drug Discovery and the Study of Protein Interactions.
Direct Binding Assays for Pharma Screening.
Chemical Genomics as an Emerging Paradigm for Postgenomic Drug Discovery.
Decrypting the Biochemical Function of an Essential Gene from Streptococcus pneumoniae using Thermofluor Technology.
Thermodynamic Stability Of Carbonic Anhydrase: Measurements Of Binding Affinity And Stoichiometry Using Thermofluor.
Design Principles for Self-Assembling Devices from Macromolecules.
A Comparison of the Chemical Properties of Drugs and FEMA/FDA Notified GRAS Chemicals used in the Food Industry.
Biochemical Bitter Blocking for New Drug Formulations.
Quantitative Assessment Of TRPM5-Dependent Oral Aversiveness Of Pharmaceuticals Using A Mouse Brief-Access Taste Aversion Assay.
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